Published 12 days ago

Take-at-home brain cancer treatment for children will soon be available on NHS

A new targeted drug therapy for brain tumors in children, dabrafenib with trametinib, approved by NICE, will now be available through the NHS for those aged 1 to 7 with specific genetic mutations.
This treatment offers a more effective and less harmful option than standard chemotherapy, with studies showing it can halt tumor growth for an average of 24.9 months, compared to 7.2 months with chemotherapy.
The therapy targets proteins from the mutated gene causing tumor growth, can be administered at home, and is approved for both low-grade and high-grade gliomas with the BRAF V600E mutation.

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The Guardian

‘Kinder’ treatment for childhood brain cancer to be offered by NHS in England

Dabrafenib with trametinib can halt growth of some tumours for more than three times as long as standard chemotherapy, study showsThe NHS is to offer children with brain tumours in England a groundbreaking new targeted drug therapy to tackle the disease – a development charities are hailing as the biggest breakthrough in decades.Gliomas are the most common type of brain cancer in children but experts say the standard treatment of chemotherapy ca…

12 days ago·London, United Kingdom

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The Independent

New NHS treatment could transform lives of thousands of children with brain tumours

Combination of dabrafenib and trametinib can now be used for patients aged one and over

12 days ago·London, United Kingdom

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The Sun

First new children's brain tumour drug for years could boost survival 18 months

CHILDREN with deadly brain tumours could get an 18-month survival boost with the first new NHS drug for almost 20 years. The medicines watchdog has approved the gene-targeting drug combination of dabrafenib and trametinib for children with glioma brain cancers. NHS12-year-old Aaliyah says she has been able to live a relatively normal life thanks to the drug combination[/caption] Around 30 critically ill children could be eligible each year in En…

12 days ago·United Kingdom

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Sky News UK

Take-at-home brain cancer treatment for children will soon be available on NHS

The combination treatment, which is given at home rather than in hospital, works by targeting the proteins made by the altered BRAF gene that is responsible for uncontrollable tumour growth.

12 days ago·United Kingdom

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